تولیدات دامی

تاثیر تغذیه یک مکمل گلوکوژنیک در اوایل زایش بر محور سوماتوتروپیک گاوهای شیری

نوع مقاله : مقاله پژوهشی

نویسندگان

رضا کریمی 1
آرمین توحیدی 2
مهدی گنج خانلو 3
سپده خویی 4
حمید قاسم زاده نوا 5
امیر علیجانی 6
محمدجواد مظفری 7

1 دانشجوی دکتری، گروه علوم دامی، پردیس کشاورزی و منابع طبیعی، دانشگاه تهران، کرج

2 استاد، گروه علوم دامی، پردیس کشاورزی و منابع طبیعی، دانشگاه تهران، کرج

3 دانشیار، گروه علوم دامی، پردیس کشاورزی و منابع طبیعی، دانشگاه تهران، کرج

4 استاد، بخش شیمی پلیمر، دانشکده شیمی، دانشگاه تهران، تهران

5 دانشیار، گروه مامایی و بیماری های تولیدمثل دام، دانشکده دامپزشکی، دانشگاه تهران

6 دستیار، گروه مامایی و بیماری های تولیدمثل دام، دانشکده دامپزشکی، دانشگاه تهران

7 دستیار گروه مامایی و بیماری های تولیدمثل دام، دانشکده دامپزشکی، دانشگاه تهران

https://doi.org/10.22059/jap.2022.339997.623679
چکیده
هدف آزمایش حاضر ارزیابی تأثیر تغذیه یک جیره گلوکوژنیک بر محور سوماتوتروپیک گاو تازه­زای هلشتاین بود. در این مطالعه از 16 راس گاو تازه­زا در قالب طرح کاملاً تصادفی با دو تیمار و هشت تکرار استفاده شد. در تیمار جیره گلوکوژنیک، گاوها روزانه 600 گرم مکمل گلوکز عبوری به‌صورت سرک دریافت می­کردند. در تیمار شاهد گاوها روزانه به­مقدار مشابهی گلوکز و مواد پوشش گلوکز عبوری (به‌طورعمده چربی) دریافت می­کردند. جیره­های آزمایشی از روز چهار تا 30 بعد از زایش تغذیه شد. مصرف ماده خشک و تولید شیر به‌صورت روزانه ثبت شد. نمونه­های خون در روزهای چهار، 15 و 29 بعد از زایش از سیاهرگ دمی گرفته شد. نتایج نشان داد از نظر مقدار تولید شیر، مقدار شیر تصحیح‌شده براساس انرژی و 5/3 درصد چربی، مصرف ماده خشک و گلوکز خون بین دو تیمار تفاوت معنی­دار وجود ندارد. جیره گلوکوژنیک سبب افزایش معنی­دار انسولین و افزایش عددی IGF-1  خون شد (05/0P<). گاوهایی که جیره شاهد دریافت کردند، کاهش معنی­داری در غلظت IGF-1 نشان دادند (05/0P<) اما این کاهش در گاوهایی که جیره حاوی مکمل گلوکوژنیک دریافت کردند مشاهده نشد. نتایج این پژوهش نشان داد تغذیه مکمل‌های گلوکوژنیک می‌تواند بر محور سوماتوتروپیک گاوهای تازه­زا اثر گذاشته و سبب افزایش بازچرخش (ترن­آور) گلوکز و افزایش انسولین خون و بهبود نسبی سطح IGF-1 خون شود.

کلیدواژه‌ها

"؛ انسولین"؛ جیره گلوکوژنیک"؛ گاو شیری"؛
"؛ گلوگز"؛
"؛ محور سوماتوتروپیک"

عنوان مقاله English

The effect of feeding a glucogenic dietary supplement during early lactation on somatotropic axis of dairy cows

نویسندگان English

Reza Karimi 1
Armin Towhidi 2
Mahdi ganjkhanlou 3
Sepideh Khoee 4
Hamid Ghasemzadeh-Nava 5
Amir Alijani 6
Mohamadjavad Mozafari 7
1 Ph.D. of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran
2 professor,, Dept. of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran
3 Associate Prof., Dept. of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran
4 Professor, Department of Polymer Chemistry, Faculty of Chemistry, University of Tehran, Tehran
5 Associate Professor, Department Theriogenology, Faculty of Veterinary Medicine, University of Tehran
6 Resident, , Department Theriogenology, Faculty of Veterinary Medicine, University of Tehran
7 Resident,و Department Theriogenology, Faculty of Veterinary Medicine, University of Tehran
چکیده English

The aim of the present experiment was to evaluate the effect of feeding a glucogenic diet on the somatotropic axis of early lactation Holstein dairy cows. Sixteen fresh cows were used in a completely randomized design with two treatments and eight replicates in each treat. In the treatment of glucogenic diet, cows received 600 g of encasulated glucose daily as top dressed. In the control treatment, the cows received daily the same amount of glucose and coating material (mainly fat). Experimental diets were fed from day 4 to 30 after calving. Milk production and dry matter intake were recorded daily. Blood samples collected on days 4, 15 and 29 after parturition from coccygeal vein. The results show that there is no significant difference between treatments in terms of milk yield, energy corrected milk yield, 3.5% fat corrected milk yield, dry matter intake and blood glucose concentration. The glucogenic diet caused a significant increase in blood insulin (P<0.05) and a numerical increase in blood IGF-1 (P<0.15). Cows that received control diet showed a significant decrease in IGF-1 concentration (P<0.05) but no significant decrease was observed for cows received diet containing glucogenic supplement. The results of this study showed that feeding a glucogenic supplements can affect the somatotropic axis of early cows and cause an increase glucose turnover and blood insulin and relative improvement of blood IGF-1 levels.
 

کلیدواژه‌ها English

"؛ dairy cow"؛
"؛ glucose"؛ glucogenic diet"؛ Insulin"؛
"؛ somatotropic axis"
  1. Amaral DM, Veenhuize JJ, Drackley JK, Cooley MH, McGilliard AD and Young JW (1990) Metabolism of propionate, glucose, and carbon dioxide as affected by exogenous glucose in dairy cows at energy equilibrium. Journal of Dairy Science 73(5): 1244-1254.
  2. Bell AW (1995) Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. Journal of animal science 73(9): 2804-2819.
  3. Brown WE and Allen MS (2013) Effects of intrajugular glucose infusion on feed intake, milk yield, and metabolic responses of early postpartum cows fed diets varying in protein and starch concentration. Journal of dairy Science 96(11): 7132-7142.
  4. Butler ST, Bork AL, Pelton SH, Radcliff RP, Lucy MC and Butler WR (2003) Insulin restores hepatic growth hormone (GH) responsiveness during lactation-induced negative energy balance in dairy cattle: effects on expression of insulin-like growth factor-I and GH receptor 1A. Journal of Endocrinology 176: 205-217.

 

 

 

 

 

 

 

  1. Clark JH, Spires HR, Derrig RG and Bennink MR (1977) Milk production, nitrogen utilization and glucose synthesis in lactating cows infused postruminally with sodium caseinate and glucose. The Journal of nutrition 107(4): 631-644.
  2. DeSouza J, Batistel F and Santos FAP (2017) Effect of sources of calcium salts of fatty acids on production, nutrient digestibility, energy balance, and carryover effects of early lactation grazing dairy cows. Journal of dairy science 100(2): 1072-1085.
  3. Ebdalabadi MN, Valizadah R, Moussavi AH, Mesgaran MD, Tahmoorespour M and Ehsani A (2014) Effects of timing to start lipogenic diet on productive and reproductive responses in periparturient dairy cows. Livestock Science 162: 104-114.
  4. Fisher LJ and Elliot JM (1966) Effect of intravenous infusion of propionate or glucose on bovine milk composition. Journal of Dairy Science, 49(7), 826-829.
  5. Garnsworthy PC, Gong JG, Armstrong DG, Mann GE, Sinclair KD and Webb R (2009) Effect of site of starch digestion on metabolic hormones and ovarian function in dairy cows. Livestock Science 125(2-3): 161-168.
  6. Knowlton KF, Dawson TE, Glenn BP, Huntington GB and Erdman R A (1998) Glucose metabolism and milk yield of cows infused abomasally or ruminally with starch. Journal of Dairy Science 81(12): 3248-3258.
  7. Larsen M and Kristensen NB (2009) Effect of abomasal glucose infusion on splanchnic and whole-body glucose metabolism in periparturient dairy cows. Journal of dairy science 92(3): 1071-1083.
  8. Lemosquet S, Rideau N, Rulquin H, Faverdin P, Simon J and Verite R (1997) Effects of a duodenal glucose infusion on the relationship between plasma concentrations of glucose and insulin in dairy cows. Journal of Dairy Science 80(11): 2854-2865.
  9. Li XP, Tan ZL, Jiao JZ, Long DL, Zhou CS, Yi KL and Han XF (2019) Supplementation with fat-coated rumen-protected glucose during the transition period enhances milk production and influences blood biochemical parameters of liver function and inflammation in dairy cows. Animal Feed Science and Technology 252: 92-102.
  10. Lucy MC (2008) Functional differences in the growth hormone and insulin‐like growth factor axis in cattle and pigs: implications for post‐partum nutrition and reproduction. Reproduction in Domestic Animals 43: 31-39.
  11. Lucy MC (2015) Mechanisms Linking Postpartum Metabolism with Reproduction in Dairy Cows. In 26th Florida Ruminant Nutrition Symposium (pp. 56-68).
  12. Lucy MC (2008) nutrient partitioning and reproductive performance in dairy cows. Dairy Nutritional Strategies to Meet Economic and Environmental Challenges, p 139.
  13. Lucy MC (2016) The role of glucose in dairy cattle reproduction. Advances in Dairy Technology28: 161-173.
  14. Lucy MC, Escalante RC, Keisler DH, Lamberson WR and Mathew DJ (2013) Glucose infusion into early postpartum cows defines an upper physiological set point for blood glucose and causes rapid and reversible changes in blood hormones and metabolites. Journal of Dairy Science 96(9): 5762-5768.
  15. McCarthy CS (2019) Evaluating the effects of rumen-protected glucose (RPG) on production, metabolism, and inflammation in transitioning dairy cows, ph.D. dissertation
  16. McCarthy CS, Dooley BC, Branstad EH, Kramer AJ, Horst EA, Mayorga EJ and Baumgard LH (2020) Energetic metabolism, milk production, and inflammatory response of transition dairy cows fed rumen-protected glucose. Journal of Dairy Science 103(8): 7451-7461.
  17. Van Knegsel ATM, Van den Brand H, Dijkstra J. Van Straalen WM, Heetkamp MJW, Tamminga S and Kemp B (2007) Dietary energy source in dairy cows in early lactation: energy partitioning and milk composition. Journal of Dairy Science 90(3): 1467-1476.
  18. Van Knegsel ATM, Van den Brand H, Graat EAM, Dijkstra J, Jorritsma R, Decuypere E and Kemp B (2007) Dietary energy source in dairy cows in early lactation: metabolites and metabolic hormones. Journal of Dairy Science 90(3): 1477-1485.
  19. Wang YP, Cai M, Hua DK, Zhang F, Jiang LS, Zhao YG and Xiong BH (2020) Metabolomics reveals effects of rumen-protected glucose on metabolism of dairy cows in early lactation. Animal Feed Science and Technology 269: 114620.
  20. Wang Y, Han X, Tan Z, Kang J and Wang Z (2020) Rumen-Protected Glucose Stimulates the Insulin-Like Growth Factor System and mTOR/AKT Pathway in the Endometrium of Early Postpartum Dairy Cows. Animals 10(2): 357.

25. Wankhade PR, Manimaran A, Kumaresan A, Jeyakumar S, Ramesha KP, Sejian V and Varghese MR (2017) Metabolic and immunological changes in transition dairy cows: A review. Veterinary world 10(11): 1367.

تولیدات دامی
دوره 24، شماره 3
پاییز 1401
صفحه 365-372

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