Document Type : Research Paper
Authors
Abstract
The aim of this study was to map body weight QTLs with some microsatellite markers on chromosome 2 of Markhoz goats. For this purpose a total of 255 offspring including 129 male and 126 female from 8 half-sib sire families were genotyped for 6 microsatellite markers on chromosomes 2. Quantitative traits were included weights at birth, 4 months, 6 months, 9 months and 12 months of age. Significant QTL effect was tested using the least squared regression approach using GridQTL (V3.3.0) software. In this study, one putative QTL were detected for weaning weight at 153 cM on chromosome 2 (P<0.01). QTL effect was 4.99 in units of residual standard deviation. The position of this QTL was between the IDVGA64 and OarFCB011 and its distance was measured 10 cM of IDVGA64 markers. In the present study any pleiotropic effect of this QTL with other traits were not recognized. It is expected that future genome wide scan with larger individual per family will help identify pleotropic effects and other QTLs associated with these traits and will provide useful markers for marker-assisted selection of such important traits. According to ensure high confidence interval (CM = 25 cM) Offer is not valid candidate genes for QTL set and is recommended for accurate determination of the QTL in future studies of more offspring in the family are applied.
Keywords
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