Document Type : Research Paper
Authors
- Danial mohsenisoltani 1
- alireza aghashahi 2
- habib aghdam shahryar 3
- yahya ebrahimnejad 4
- sayed abdoullah hosseini 5
1 Islamic Azad university of Shabestar.
2 department of animal and poultry nut.Iran animal science nutrition.areeo.Iran
3 Islamic Azad University of Shabestar
4 Islamic Azad Un.of shabestar
5 Animal Sceince Reaserch Institute
Abstract
This study was conducted to investigate the effects of toxin binders and prebiotics on growth performance, intestinal microbial population, stress and antioxidant indexes of broiler chicks fed diets contaminated with aflatoxin B1. In this study, 600 1-d-old mixed broiler chicks (Ross 308) were investigated in 10 treatments with 6 replications and 10 chicks per replication. Experimental treatments included: Negative controls un-supplemented and supplemented with ASRI1 and ASRI2 toxin binders and prebiotic and positive groups un-supplemented and supplemented with ASRI1 and ASRI2 toxin binders and prebiotic, ASRI1 +prebiotic and ASRI2 +prebiotic. Growth performance, stress indexes of heterophile, lymphocyte, bacterial population and stress indexes of super oxide dismutase (SOD), glutathione peroxidase (GPx) and malondialdehyde (MDA) were investigated. Dietary inclusion of aflatoxin into diet increased heterophile, heterophile:lymphocyte ratio and decreased lymphocyte (P<0.05), but toxin binders and prebiotic alleviated effects of aflatoxin on heterophile and lymphpocyte. Thepopulation of E. coli and lactobacilli were significantly higher and lower in positive control compared to negative control (P < 0.05). The results also showed that the serum concentrations of antioxidant enzymes were significantly lower in negative control compared to positive control (P < 0.05). In sum, aflatoxin showed negative effects on growth performance, intestinal microbial populations, stress and antioxidant indexes but toxin binders and prebiotic decreased its negative effects and inclusion of ASRI1(3kg/ton) was better than other toxin binders.
Keywords
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