Document Type : Research Paper
Authors
- Abbas Rajaeerad 1
- Gholam Reza Ghorbani 2
- Mohammad Khorvash 2
- Ali Sadeghi-Sefidmazgi 3
- Amir Hossein Mahdavi 4
- Masoud Boroumand Jazi 5
- Mirja Rosmarie Wilkens 6
1 Ph.D. student, Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan, Iran
2 Professor, Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan, Iran.
3 Associate Professor, Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan, Iran
4 Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, Iran
5 Researcher, Animal Science Research Department, Isfahan Agricultural and Natural Resources Research and Education Center, Agricultural Research, Education and Extension Organization(AREEO), Isfahan, Iran.
6 Researcher, Institute of Physiology and Cell Biology, University of Veterinary Medicine of Hannover, Hannover, Germany
Abstract
The effects of different levels of mild metabolic acidosis by anionic diet on the performance of transition dairy cows were investegieted in 12 cows from 3 weeks (wk) before calving. One wk before calving, cows assigned to two groups according to urine pH (UpH) to recommended level (R UpH=6.2 to 7) and less than 6.3 (low UpH). The average prepartum urine pH was 6.7 and 5.8 for R UpH and low UpH groups, respectively (P<0.01). The prepartum serum concentration of Ca was not affected by the experimental groups, but significantly increased in the low UpH group within 2 h after calving. A trend was observed for higher serum concentration of phosphorus in the low UpH cows before calving. Although no significant difference was observed in prepartum DMI, but postpartum DMI and milk production were higher during wk 1 after calving in low UpH group (P<0.05). Total concentrations of protein and globulin were decreased on the day before calving in low UpH group. Also, after calving the concentrations of BUN, total protein, globulin, and milk protein were lower in this group of cows (P<0.05). Therefore, the induction of higher levels of metabolic acidosis in comparison to the recommended level before calving, can improve serum concentration of Ca and performance of transition cows.
Keywords
KE, Godden S, Capel M, Santos JEP, Overton
MWand Duffield TF (2012) The association of
serum metabolites in the transition period with
milk production and early-lactation
reproductive performance. Journal of Dairy
Science 95: 1301-1309.
2. Charbonneau E, Pellerin D and Oetzel G.R
(2006) Impact of Lowering Dietary Cation-Anion
Difference in Nonlactating Dairy Cows: A Meta-
Analysis. Journal of Dairy Science 89: 537-548.
Staufenbiel R, and Sample HR (2009)
Application of strong ion difference theory to
urine and the relationship between urine pH
and net acid excretion in cattle. American
Journal of Veterinary Research 70: 915-925.
4. Curthoys NP and Moe OW (2014) Proximal
tubule function and response to acidosis.
Clinical journal of the American Society of
Nephrology 9: 1627-1638.
5. Daniel RC (1983) Motility of the rumen and
abomasum during hypocalcaemia. The Canadian
journal of Comparative Medicine 47: 276-280.
6. Espino L, Suarez ML, Santamarina G, Goicoa
A and Fidalgo LE (2005) Effects of Dietary C
ation–Anion Difference on Blood Cortisol and
ACTH Levels in Reproducing Ewes. Journal
of Veterinary Median 52: 8-12.
7. Glosson KM, Zhang X, Bascom SS, Rowson
AD, Wang Z, and Drackley JK (2020)
Negative dietary cation-anion difference and
amount of calcium in prepartum diets: Effects
on milk production, blood calcium, and health,
Journal of Dairy Science 103: 7039-7054.
8. Goff JP (2008) The monitoring, prevention,
and treatment of milk fever and subclinical
hypocalcemia in dairy cows. Veterinary
Journal 176: 50-57
9. Goff JP, Liesegang A and Horst RL (2014)
Diet-induced pseudohypoparathyroidism: A
hypocalcemia and milk fever risk factor.
Journal of Dairy Science 97: 1520-1528.
10. Goff JP, Ruiz R and Horst RL (2004) Relative
Acidifying Activity of Anionic Salts
Commonly Used to Prevent Milk Fever.
Journal of Dairy Science 87: 1245-1255.
11. Grummer RR, Mashek DG, and Hayirli A (2004 )
Dry matter intake and energy balance in the
transition period. Veterinary Clinics of North
America: Food Animal Practice 20: 447-470.
12. Grünberg W, Donkin SS and Constable PD
(2011) Periparturient effects of feeding a low
dietary cation-anion difference diet on acidbase,
calcium, and phosphorus homeostasis
and on intravenous glucose tolerance test in
high-producing dairy cows. Journal of Dairy
Science 94: 727-745.
13. Krapf R, Jaeger P and Hulter HN (1992) Chronic
respiratory alkalosis induces renal resistance,
hyperphosphatemia and hypocalcemia in
humans. Kidney Internal 42: 727-734.
14. Lean IJ, Santos JEP, Block E and Golder HM
(2019) Effects of prepartum dietary cationanion
difference intake on production and
health of dairy cows: A meta-analysis. Journal
of Dairy Science 102: 2103-2133.
15. Leno BM, Ryan CM, Stokol T, Kirk D,
Zanzalari KP, Chapman JD and Overton TR
(2017) Effects of prepartum dietary cationanion
difference on aspects of peripartum
mineral and energy metabolism and
performance of multiparous Holstein cows.
Journal of Dairy Science 100: 4604-4622.
16. Mackle TR, Dwyer DA, Ingvartsen KL,
Chouinard PY, Ross DA and Bauman DE
(2000) Evaluation of whole blood and plasma
in the interorgan supply of free amino acids for
the mammary gland of lactating dairy cows.
Journal of Dairy Science 83: 1300-1309.
17. Martinez N, Risco CA, Lima FS, Bisinotto RS,
Greco LF, Ribeiro ES, Maunsell F, Galvão K
and Santos JEP (2012) Evaluation of peripartal
calcium status, energetic profile, and
neutrophil function in dairy cows at low or
high risk of developing uterine disease. Journal
of Dairy Science 95: 7158-7172.
18. Martinez N, Rodney RM, Block E, Hernandez
L, Nelson CD, Lean J and Santos JEP (2018)
Effects of prepartum dietary cation-anion
difference and source of vitamin D in dairy
cows: Lactation performance and energy
metabolism. Journal of Dairy Science 101:
2544-2562.
19. Martinez N, Sinedino LD, Bisinotto PRS,
Ribeiro ES, Gomes GC, Lima FS, Greco LF,
Risco CA, Galvão KN, Taylor-Rodriguez D,
Driver JP, Thatcher WW and Santos JEP
(2014) Effect of induced subclinical
hypocalcemia on physiological responses and
neutrophil function in dairy cows. Journal of
Dairy Science 97: 874-887.
20. Ramos-Nieves JM, Thering BJ, Waldron MR,
Jardon PW and Overton TR (2009) Effects of
anion supplementation to low-potassium
prepartum diets on macromineral status and
performance of periparturient dairy cows.
Journal of Dairy Science 92: 5677-5691.
21. Reinhardt TA, Lippolis JD, McCluskey BJ,
Goff JP and Horst RL (2011) Prevalence of
subclinical hypocalcemia in dairy herds.
Veterinary Journal 188: 122-124.
22. Santos JEP, Golder HM, Block E and Lean IJ
(2019) Meta-analysis of the effects of
prepartum dietary cation-anion difference on
performance and health of dairy cows. Journal
of Dairy Science 102: 2134-2154.
23. Shirazi-Beechey SP, Beechey RB, Penny J,
Vayro S, Buchan W and Scott D (1991)
intestine and parotid gland: response to
variation in dietary phosphate supply.
Experimental Physiology 76: 231-241.
24. Van Soest PJ, Robertson JB and Lewis BA
(1991) Methods for Dietary Fiber, Neutral
Detergent Fiber, and Nonstarch Polysaccharides
in Relation to Animal Nutrition. Journal of Dairy
Science 74: 3583-3597.
25. Zimpel R, Poindexter MB, Vieira-Neto A,
Block E, Staples CR, Thatcher WW and
Santos JEP (2018) Effect of dietary cationanion
difference on acid-base status and dry
matter intake in dry cows. Journal of Dairy
Science 101: 8461-8475.
)